CDC Recommends 2-Dose Monkeypox Vaccine Despite a ‘Small’ Risk

A two-dose vaccination for monkeypox is now recommended for high-risk adults in the event of a monkeypox outbreak and that could be as small as a single case—at the discretion of local health authorities—the U.S. Centers for Disease Control (CDC) said on Feb. 22.
The CDC’s Advisory Committee on Immunization Practices unanimously approved the recommendation for the vaccine Jynneos despite the fact that potentially serious health risks could not definitively be ruled out.
Jynneos was approved by the U.S. Food and Drug Administration (FDA) in 2019. Nearly 1.2 million doses have been administered since May 2022.
The U.S. Centers for Disease Control and Prevention (CDC) headquarters in Atlanta, Ga., on Sept. 30, 2014. (Tami Chappell/Reuters)
The CDC recommendation indicates that two doses are needed, to be administered one month apart and that it takes two weeks after the second dose for the vaccine to be most effective….}

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